Androgens synthesized in the ovaries are converted to estradiol in which ovarian cell type?

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Multiple Choice

Androgens synthesized in the ovaries are converted to estradiol in which ovarian cell type?

Explanation:
Within the ovarian follicle, androgens produced by the theca interna under LH stimulation are handed off to granulosa cells, which express the enzyme aromatase. Aromatase converts these androgens into estrogens, mainly estradiol, with granulosa cells being the site of this conversion under the influence of FSH. The oocyte itself doesn’t perform this aromatization. Thus, granulosa cells are the cells that convert androgens to estradiol in the ovary.

Within the ovarian follicle, androgens produced by the theca interna under LH stimulation are handed off to granulosa cells, which express the enzyme aromatase. Aromatase converts these androgens into estrogens, mainly estradiol, with granulosa cells being the site of this conversion under the influence of FSH. The oocyte itself doesn’t perform this aromatization. Thus, granulosa cells are the cells that convert androgens to estradiol in the ovary.

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