What histologic feature distinguishes elastic cartilage from hyaline cartilage?

Study for the NBME Histology Test. Access flashcards and multiple choice questions, each with hints and explanations. Prepare effectively for your exam!

Multiple Choice

What histologic feature distinguishes elastic cartilage from hyaline cartilage?

Explanation:
The key histologic difference is the composition of the extracellular matrix. Elastic cartilage contains a dense network of elastic fibers within its matrix, which can be highlighted with special stains and gives the tissue more elasticity. Hyaline cartilage, on the other hand, has a smooth, homogeneous (glassy) matrix with sparse or no elastic fibers, composed mainly of type II collagen and proteoglycans. This contrast in matrix fibers is what makes elastic cartilage distinguishable from hyaline cartilage: elastic cartilage shows numerous elastic fibers in the matrix, while hyaline cartilage has a glassy, fiber-poor matrix. The presence of perichondrium can occur with both, so that feature is not the distinguishing factor here.

The key histologic difference is the composition of the extracellular matrix. Elastic cartilage contains a dense network of elastic fibers within its matrix, which can be highlighted with special stains and gives the tissue more elasticity. Hyaline cartilage, on the other hand, has a smooth, homogeneous (glassy) matrix with sparse or no elastic fibers, composed mainly of type II collagen and proteoglycans. This contrast in matrix fibers is what makes elastic cartilage distinguishable from hyaline cartilage: elastic cartilage shows numerous elastic fibers in the matrix, while hyaline cartilage has a glassy, fiber-poor matrix. The presence of perichondrium can occur with both, so that feature is not the distinguishing factor here.

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