What histological features define the adrenal medulla?

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Study for the NBME Histology Test. Access flashcards and multiple choice questions, each with hints and explanations. Prepare effectively for your exam!

Multiple Choice

What histological features define the adrenal medulla?

Explanation:
Adrenal medulla is defined histologically by chromaffin cells that are organized in cords around capillaries. These neural crest–derived neuroendocrine cells store and rapidly secrete catecholamines (epinephrine and norepinephrine) in response to sympathetic stimulation. The name chromaffin comes from their staining: these cells take up chromium salts and appear brown on chromaffin staining, reflecting their catecholamine content. This makes the medulla distinct from the cortex, which consists of steroid-secreting zones (glomerulosa, fasciculata, reticularis). The other descriptions point to cortical tissue or unrelated tissue, not the medulla.

Adrenal medulla is defined histologically by chromaffin cells that are organized in cords around capillaries. These neural crest–derived neuroendocrine cells store and rapidly secrete catecholamines (epinephrine and norepinephrine) in response to sympathetic stimulation. The name chromaffin comes from their staining: these cells take up chromium salts and appear brown on chromaffin staining, reflecting their catecholamine content. This makes the medulla distinct from the cortex, which consists of steroid-secreting zones (glomerulosa, fasciculata, reticularis). The other descriptions point to cortical tissue or unrelated tissue, not the medulla.

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